Description
Product Characteristics:
SLC23A3 (Solute Carrier Family 23, Member 3) is a Protein Coding gene. Diseases associated with SLC23A3 include epilepsy, generalized, with febrile seizures plus, type 5. GO annotations related to this gene include transporter activity. An important paralog of this gene is SLC23A1.
Subcellular location: Cell membrane
Synonyms: Solute carrier family 23 member 3, SLC23A3, Solute carrier family 23 member 3, HPC E2-binding protein 3, Na(+)/L-ascorbic acid transporter 3, Sodium-dependent vitamin C transporter 3, SLC23A3, E2BP3, SVCT3
Target Information: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]